In celebration of Route 66's 100th anniversary, Loews Hotels in St. Louis, Chicago, and O'Hare invite you to experience the first stretch of the Mother Road in a whole new way. From St. Louis to Chicago, discover exclusive stays, nostalgic dining pop-ups, curated road trip perks, and can't-miss partnerships that bring the journey to life. Get your kicks on Loews 66 this summer and explore two iconic cities connected by one unforgettable road.